Associate Professor
Year Started at JMU: 2016
walke2mx@jmu.edu
Contact Info
Research Description
The research focus of my laboratory is understanding vision loss in retinal degenerative diseases. We study the pathophysiology of photoreceptors including intrinsically photosensitive retinal ganglion cells (ipRGCs) in mouse retinal degeneration models. Our goal is to identify key molecular pathways that underlie photoreceptor cell death and test if these pathways provide potential targets for future retinal therapies.
Office Hours
Education
- PhD in Biological Sciences (Visual Neuroscience), 2008, University of Maryland Baltimore County, Baltimore, MD
- MS in Biology, 1993, Morgan State University, Baltimore,MD
Select Publications
- Walker, M. T. and Montell, C. “Suppression of the motor deficit in a mucolipidosis type IV mouse model by bone marrow transplantation” 2016 Hum Mol Genet 25 (13): 2752-2761
- Montell, C. “RdgB2 is required for dim-light input into intrinsically photosensitive retinal ganglion cells.” 2015 Mol Biol Cell Oct. 15; 26 (20): 3671-8
- Walker, M. T.; Brown, R. L.; Cronin, T. W.; Robinson, P. R. ”Photochemistry of retinal chromophore in mouse melanopsin.” 2008 Proc Natl Acad Sci USA 105: 8861-5.